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were collected from Zhoushan city, Zhejiang province。我是不懂轮子还是冠状，不过这么多从舟山抓来的蝙蝠莫非都是他们发疯了抓来黑李洪志的？注意你的人设

benii(惊坐起)
本文发表在 rolia.net 枫下论坛Abstract

SARS coronavirus (SARS-CoV), the causative agent of the large SARS outbreak in 2003, originated in bats. Many SARS-like coronaviruses (SL-CoVs) have been detected in bats, particularly those that reside in China, Europe, and Africa. To further understand the evolutionary relationship between SARS-CoV and its reservoirs, 334 bats were collected from Zhoushan city, Zhejiang province, China, between 2015 and 2017. PCR amplification of the conserved coronaviral protein RdRp detected coronaviruses in 26.65% of bats belonging to this region, and this number was influenced by seasonal changes. Full genomic analyses of the two new SL-CoVs from Zhoushan (ZXC21 and ZC45) showed that their genomes were 29,732 nucleotides (nt) and 29,802 nt in length, respectively, with 13 open reading frames (ORFs). These results revealed 81% shared nucleotide identity with human/civet SARS CoVs, which was more distant than that observed previously for bat SL-CoVs in China. Importantly, using pathogenic tests, we found that the virus can reproduce and cause disease in suckling rats, and further studies showed that the virus-like particles can be observed in the brains of suckling rats by electron microscopy. Thus, this study increased our understanding of the genetic diversity of the SL-CoVs carried by bats and also provided a new perspective to study the possibility of cross-species transmission of SL-CoVs using suckling rats as an animal model.更多精彩文章及讨论，请光临枫下论坛 rolia.net
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Last Updated: 2020-8-8
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Replies, comments and Discussions:

  • 枫下沙龙 / 谈天说地 / 这是2020年1月25日，在119之后，全世界第一个用英文写出来的关于病毒来自实验室的部分线索证据，当时一天点击率就4万多！这个文章就是美女英雄科学家闫丽梦博士写的，首先发给了路德先生，路德发给Sara，Sara就把它刊登在GNEWS上了。 -111111(快乐老家); 2020-8-8 {57} (#13130188@0) +1

     

    • Brief summary of evidence of lab-made 2019 nCoV -111111(快乐老家); 2020-8-8 {181} (#13130193@0)
      From 2017-2019, a series academic papers about a novel zoonotic coronavirus isolated from bats in Zhoushan, Zhejiang (in short, ZS bat-CoV) were published in English (1) and Chinese
      • 证据就这个？生物信息搞什么序列比对就是笑话，搞文章灌灌水还可以，与真实世界差距无穷远。如果闫博士只有这些“证据”，那就真是闹笑话了。这些都是公开发表的论文。 -34weston(Aaron); 2020-8-8 (#13130200@0) +3
        • 你是学习生物的？ -111111(快乐老家); 2020-8-8 (#13130220@0) +7
          • 他还觉得浏览器一通江湖 -stayhome(stayhome); 2020-8-8 (#13130317@0) +3
          • 他什么都学，百事通，哈哈。因为背后有强大的祖国支持广大的网络评论员 -lovesports(wow); 2020-8-8 (#13130356@0) +5
      • 舟山的是轮（毒运轮的轮，哈哈。Rotavirus）状病毒，闫博士能否讲讲与冠状病毒的联系？？ -tartarus(Dark); 2020-8-8 (#13130233@0) +2
        • 不要轮状病毒和冠状病毒也闹不清楚，那就是大笑话了。。。 -tartarus(Dark); 2020-8-8 (#13130237@0) +1
          • were collected from Zhoushan city, Zhejiang province。我是不懂轮子还是冠状，不过这么多从舟山抓来的蝙蝠莫非都是他们发疯了抓来黑李洪志的？注意你的人设 -benii(惊坐起); 2020-8-8 {1454} (#13130354@0) +2
            本文发表在 rolia.net 枫下论坛Abstract

            SARS coronavirus (SARS-CoV), the causative agent of the large SARS outbreak in 2003, originated in bats. Many SARS-like coronaviruses (SL-CoVs) have been detected in bats, particularly those that reside in China, Europe, and Africa. To further understand the evolutionary relationship between SARS-CoV and its reservoirs, 334 bats were collected from Zhoushan city, Zhejiang province, China, between 2015 and 2017. PCR amplification of the conserved coronaviral protein RdRp detected coronaviruses in 26.65% of bats belonging to this region, and this number was influenced by seasonal changes. Full genomic analyses of the two new SL-CoVs from Zhoushan (ZXC21 and ZC45) showed that their genomes were 29,732 nucleotides (nt) and 29,802 nt in length, respectively, with 13 open reading frames (ORFs). These results revealed 81% shared nucleotide identity with human/civet SARS CoVs, which was more distant than that observed previously for bat SL-CoVs in China. Importantly, using pathogenic tests, we found that the virus can reproduce and cause disease in suckling rats, and further studies showed that the virus-like particles can be observed in the brains of suckling rats by electron microscopy. Thus, this study increased our understanding of the genetic diversity of the SL-CoVs carried by bats and also provided a new perspective to study the possibility of cross-species transmission of SL-CoVs using suckling rats as an animal model.更多精彩文章及讨论，请光临枫下论坛 rolia.net
            • 不懂还要装懂？闫博士拿轮状病毒的东西，来当冠状病毒来ACCUSE 冠状病毒很有道理是吗？ -tartarus(Dark); 2020-8-8 (#13130444@0) +1
              • 你去跟美女英雄科学家PK吧。我就是传谣，停不下来，不要怪我无理。 -111111(快乐老家); 2020-8-8 (#13130535@0)
            • ...It means the novel ZS bat-CoV was owned by Chinese military labs only. In the papers above, they have clarified that ZS bat-CoV has potential cross-species... -tartarus(Dark); 2020-8-8 (#13130450@0) +1
    • 当然，可以考虑让老家背锅。。。 -tartarus(Dark); 2020-8-8 (#13130330@0) +1
      • 还有你们最爱的李洪志嘛。为贵组织背锅20年了 -benii(惊坐起); 2020-8-8 (#13130357@0) +1
      • 还有个办法就是牺牲博士了，嫁祸土共。。。不过可惜了，这么年轻的生命。。。 -tartarus(Dark); 2020-8-8 (#13130487@0)
    • 真是小人物也改变了历史，不过加国粉红你们天天的聒噪也是今天中美交恶的原因，也厉害 -kw23(kw23); 2020-8-8 (#13130370@0) +8

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